The "stay at home" order in Wales will be lifted and replaced by a "stay local" message this weekend - with people allowed to socialise outdoors in small groups.
From Saturday, four people from two households will be able to meet outdoors to socialise, including in gardens.
Under the Welsh government's phased approach to lifting lockdown, non-essential retail can return from 22 March as restrictions are lifted on what can be sold in shops that are already open. Garden centres will also be able to reopen.
All shops will be able to welcome customers from 12 April - the same date as in England.
In an announcement on Friday, Mr Drakeford will say: "We are taking a phased approach to unlocking each sector - starting with schools.
"We will make step-by-step changes each week to gradually restore freedoms.
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